12 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... #Hyperkalemia #
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... #Potassium #Binding ... Comparison #Table #Pharmacology ... #Patiromer #HyperKalemia
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology
Beta Blocker Side Effects / Toxicity
Cardiac Side Effects:
 • Sinus bradycardia, AV block, Heart failure exacerbation,
Side Effects / Toxicity ... Facilitation of hyperkalemia ... #SideEffects #Toxicity ... AdverseEffects #pharmacology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... works by directly binding ... - Hyperkalemia ( ... effect of digoxin toxicity ... , in states of hypokalemia
Summary of the adverse effects associated with the use of trimethoprim–sulfamethoxazole

Mnemonic - NOT RISKY?

N - Neurologic
- Reproductive toxicity ... - Sugar K - Hyperkalemia ... #SideEffects #Pharmacology
Reported Mechanisms and Toxicity of Investigational Treatments for SARS-COV-2
Chloroquine and Hydroxychloroquine
 • Mechanisms: Interference with ligand
Mechanisms and Toxicity ... Interference with ligand binding ... decreased viral budding ... myocardial depression, hypokalemia ... 3 response • Toxicity
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Hypertriglyceridemia • Hyperkalemia ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
this pathway, ending ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Is Dangerous in Hyperkalemia ... transcellular shift ... NS #comparison #pharmacology