18 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... #Hyperkalemia #
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... #Potassium #Binding ... #KBinders #Kayexelate ... Comparison #Table #Pharmacology ... #Patiromer #HyperKalemia
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
: Treatment of Hyperkalemia ... who have chronic hyperkalemia ... carry the risk of hyperkalemia ... #KBinder #Hyperkalemia ... #Pharmacology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... require phosphate binding ... aluminum-based phosphate binder ... restricted due to hypercalcemia ... #Dose #Dosing #Pharmacology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... cyclosilicate #Potassium #Binders ... #Management #Hyperkalemia ... #treatment #pharmacology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... works by directly binding ... - Hyperkalemia ( ... Because digoxin binds ... , in states of hypokalemia
Beta Blocker Side Effects / Toxicity
Cardiac Side Effects:
 • Sinus bradycardia, AV block, Heart failure exacerbation,
Side Effects / Toxicity ... Facilitation of hyperkalemia ... #SideEffects #Toxicity ... AdverseEffects #pharmacology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... • Consider K+ binder ... blocks, QRS axis shift ... , asystole #hyperkalemia
Summary of the adverse effects associated with the use of trimethoprim–sulfamethoxazole

Mnemonic - NOT RISKY?

N - Neurologic
- Reproductive toxicity ... - Sugar K - Hyperkalemia ... #SideEffects #Pharmacology