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signs growthhormone acromegaly algorithm alternating bilateral causes centralretinalartery chronic clinical complications crao enophthalmos excess exophthalmos feedbackloop floaters hypertensive management occlusion
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... lipolysis Signs/Symptoms ... : - Short ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... malignancy Pathophysiology ... Differential Diagnosis ... #Management #Endocrinology ... #Treatment #Pathophysiology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis ... Cushing's Disease • GH ... #ShortStature #Differential ... #Diagnosis #Algorithm ... #endocrinology
Xeropthalmia: Pathogenesis and Ocular Manifestations Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
-> Cotton-wool Spots ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
-> Cherry-red spot ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Floaters - Differential Diagnosis Framework What? Vitreous Floaters: • Microscopic collagen fibers within the vitreous that tend to clump
Floaters - Differential ... Diagnosis Framework ... the vision • Spots ... Retinal Detachment: Symptoms ... #ophthalmology
Intermittent Bilateral Exophthalmos (Alternating Exophthalmos and Enophthalmos) on Physical Exam Observing this patient in silence for a
Patient underwent a diagnostic ... Existing case reports ... patient- bilateral symptoms ... Differentials for ... clinical #video #ophthalmology
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