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diagnosis differential management neurology causes hypokalemia metabolic treatment acidosis algorithm alkalosis anion associated barre bartter dementia disorder encephalopathy epithelial fanconi
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Renal Tubular Defects ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... ascending limb Gitelman ... tubule Liddle syndrome ... Epithelial #Inherited #Defects ... #Kidney #Nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
of hypokalemia starts ... , Gitelman's syndrome ... acid, Liddle's syndrome ... • Cushing's syndrome ... algorithm #causes #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... Hypocalciuria (spot ... #nephrology #management ... #pathophysiology
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK Glycols - ethylene and propylene glycol Oxoproline
associated with short ... bowel syndrome ... underexcretion of acids ... GOLDMARK #mnemonic #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Severe Cushing syndrome ... tubule reabsorptive defect ... furosemide-like lesion) • Gitelman ... syndrome (defective ... Diagnosis #Causes #nephrology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Summary Acute AIDP ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... management #treatment #neurology
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology Risk factors: - Low CD4 count - Disseminated OI -
Reconstitution Inflammatory Syndrome ... (IRIS) - Pathophysiology ... OI (in CM) - Short ... #Inflammatory #Syndrome ... #AIDS
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... Etiology: • Pathophysiology ... Seizures: Treat with AEDs ... diagnosis #management #neurology
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