14 results
Hypophosphatemia Diagnostic Algorithm
- GI Losses
- Redistribution
- 1° HPT
- 1° Renal PO4 wasting: Hereditary, TIO, Fanconi Syndrome,
Hypophosphatemia ... - 1° Renal PO4 wasting ... , TIO, Fanconi Syndrome ... #phosphorus #low ... #differential #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... alkalosis, Hungry bone syndrome ... Tumor genesis syndrome ... FGF-23: Fanconi syndrome ... #phosphate #nephrology
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
Regorafenib • Hypophosphatemia ... Ifosfamide - Fanconi syndrome ... Panitumumab- renal wasting ... Trastuzumab • Hyponatremia ... Ifosfamide - Fanconi syndrome
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Appropriately Low ... Shift: Refeeding Syndrome ... Tumor Genesis Syndrome ... FGF23: Fanconi Syndrome ... #phosphorus #workup
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... • Euvolemic (Low ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... #Algorithm #nephrology
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup ... Extravascular deposition: Hyperphosphatemia ... metastases, Hungry bone syndrome ... #Hypocalcemia #Workup ... Diagnosis #Algorithm #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Cirrhosis, Nephrotic syndrome ... Cerebral salt wasting ... Primary polydipsia, Low ... diagnosis #sodium #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Cerebral salt wasting ... Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... #nephrology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
Irritable Bowel Syndrome ... Diagnosis and Workup ... cultures, but test ... /o red flags - Low ... Irritable #Bowel #Syndrome
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
can be high or low ... Cerebral Salt Wasting ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia), Low ... table #sodium #nephrology