1149 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and ... Plasma-Cell Leukemia ... revealed 25% plasma cells ... Clinical #HONC #Derm #Plasmacytomas
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Solitary Cell Plasmacytoma ... • Plasma cell neoplasms ... MM, the plasma cell ... arises from plasma cells ... from the plasma cells
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
), basophilia, plasmacytosis ... predominant immature cells
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
marrow plasma cell ... • CML, B and T cell ... amyloidosis, solitary plasmacytoma
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
myeloma • Plasma cell ... leukemia • Solitary plasmacytoma ... syndrome) • Solitary plasmacytoma ... Thalassemia, Sickle cell
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... smear: Smudge cells ... or basket cells ... disease • B cell ... AIHA • Pure red cell
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... promote dendritic cell ... These T cells then ... induce B-cell class ... induce goblet cell
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Involvement - B-cell ... CD10 - T-cell ... or λ), Smudge Cells ... - B-cell ... Thrombocytosis - T-cell
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Activated T cells ... responses, and B cells ... antigen activates B cells ... binding to the B-cell ... binding to the T-cell
B/T Cell Development
This is a work in progress describing the maturation of B & T cells
B/T Cell Development ... maturation of B & T cells ... more to the T cells ... #lymph node #b-cell ... #t-cell