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hematology sle treatment druginduced erythematosus product reactions summary systemic approach arthritis cerebritis classification cns comparison differential dil hemophagocytic hlh hodgkins
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar ... • Immunologic Workup ... Positive in 60-80% of cases ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... • Immunologic Workup ... Discontinuation of causal ... comparison #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... thrombosis and/or blood-brain ... permeability Diagnosis ... CNS #neurology #rheumatology ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Leishmaniosis, malaria ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... spondyloarthropathies, lupus ... Like in this case ... Joint #Pain #MSK #rheumatology ... #approach #workup
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
& NPSLE rare, Malar ... • Immunologic Workup ... #DIL #rheumatology ... #diagnosis #treatment ... #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... tested include: Malaria ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... tested include: Malaria ... #Transfusions #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... : • Full Blood ... lymph node biopsy (diagnostic ... marrow biopsy - if blood ... #oncology #management
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