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diagnosis hematology differential erythematosus management sle arthritis autoantibodies hemeonc hemophagocytic hlh laboratory lymphohistiocytosis macrophage mimickers monoclonal oncology paraproteinemias rheumatic rheumatoid
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... • Systemic lupus ... lupus erythematosus ... with leukopenia, anemia ... #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Arthritis 69% - Malar ... - Hemolytic anemia ... sclerosis, Still's disease ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... (NPSLE): • May ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... myopathy • Anti MAG ... (-) hemolytic anemia ... to cold IgG • Lupus ... Sneddon-Wilkinson disease
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... lupus erythematosus ... the presence of anemia ... diagnosis #testing #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... ▪ Autoimmune diseases ... (often termed MAS-HLH ... - Cytopenias (anemia ... Diagnosis #Management #Hematology
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