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hematology management differential product reactions treatment workup abscess arthritis disorders erythematosus extravascular fever hemolysis hemolytic hemophagocytic hlh infectiousdiseases intravascular laboratory
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #hematology #anemia
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management Summary ... Manifestations: Malar ... Evolution: Chronic disease ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... plateletcount), peripheral blood ... smear, HIV/HCV testing ... changes), high MCV anemia ... #hematology
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... Babesiosis • Plasmodium ... of malaria diagnosed ... during the U.S. summer ... renal function • Blood
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Leishmaniosis, malaria ... Drugs, Unknown cause ... management #treatment #summary ... #rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management Summary ... • Most common cause ... Leukocytosis, anemia ... • Sputum/Blood ... #differential #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Myeloproliferative Disease ... Treatment: Goals: Treating ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
One Pager Summary ... Crossmatch - involves testing ... false negatives on testing ... tested include: Malaria ... #Transfusions #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... the presence of anemia ... : • Complete blood ... #testing #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... false negatives on testing ... tested include: Malaria ... #Transfusion #diagnosis ... #management #hematology
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