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Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Arthritis 69% - Malar ... rash 40% - Fever ... - Hemolytic anemia ... autoantibodies #signs ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... pain (20%) Renal disease ... (75%): Anemia ( ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
No hemolytic anemia ... Babesiosis • Plasmodium ... renal function • Blood ... a chest film; blood-smear ... and possibly PCR testing
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... S/sx: Fever, flank ... Causes purpura & ... false negatives on testing ... tested include: Malaria
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... Causes purpura & ... Sx include: fever ... false negatives on testing ... tested include: Malaria
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... such as systemic lupus ... purpura: strong sign ... Large Vessel: Blood ... differential #diagnosis #rheumatology