9 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
(SLE), Systemic ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Anti-phospholipid) M Malar ... Discoid Rash A Antinuclear ... Antibody (ANA) ... #IMDAMNSHARP #sle ... #systemic #lupus
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... (SLE), Systemic ... (SLE), Systemic ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... autoantibodies #Systemic ... #diagnosis #rheumatology ... #table #ANA
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Arthritis 69% - Malar ... Diagnosis and Lupus ... #Systemic #Lupus ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... & NPSLE rare, Malar ... months to years) Systemic ... Workup: - ANA ... #table #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Photosensitivity • Malar ... : • Symptoms limited ... #Systemic #Lupus
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... presentation of systemic ... lupus erythematosus ... #Pericarditis #Symptoms ... Presentation #comparison #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... lupus erythematosus ... Symptoms (Sx) in ... SLE) • Urinalysis ... #diagnosis #rheumatology