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diagnosis hematology druginduced hemophagocytic lymphohistiocytosis sle summary activation comparison dil erythematosus hodgkins lymphoma macrophage mas nephritis nephrology oncology syndrome systemic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Management Summary ... Manifestations: Malar ... Workup: - ANA ... life-threatening • Treatment ... #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Leishmaniosis, malaria ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
• Bicytopenia Treatment ... • Infection should ... antibiotic therapy should ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... #treatment #management ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Workup: - ANA ... Manifestations: Malar ... Workup: - ANA ... comparison #table #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... Hodgkin Lymphoma Treatment ... lymphoma #diagnosis #classification ... #hematology #oncology ... #management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
& NPSLE rare, Malar ... Workup: - ANA ... #DIL #rheumatology ... #diagnosis #treatment ... #management
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