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diagnosis differential hematology hemolytic pediatrics peds algorithm bleeding classification hemolysis hemostasis intravascular limping nwb pathway purpura thrombocytopenia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #diagnosis #hematology ... #anemia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... : • Liver disease ... Bartonella, Babesia, Malaria ... IVIG infusion Intravascular ... classification #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
NON-WEIGHT BEARING CHILD ... FLAGS - In all cases ... and these should ... sweats, pallor, bruising ... Rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... SLE (systemic lupus ... Congenital heart disease ... #Causes #peds #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... inhibitor and lupus ... of factor VII should ... discern these causes ... #Bleeding #Bruising
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