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diagnosis differential hematology autoantibodies bleeding erythematosus extravascular hemolysis hemolytic hemostasis intravascular management mimickers pediatrics peds pmr polymyalgia purpura rheumatica sle
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes ... #anemia
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... - Hemolytic anemia ... sclerosis, Still's disease ... autoantibodies #signs ... #differential #rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... SLE (systemic lupus ... Congenital heart disease ... #Causes #peds #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... inhibitor and lupus ... of factor VII should ... discern these causes ... #Bleeding #Bruising
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
of unknown cause ... motion in the shoulders ... describe difficulty rising ... • Normocytic anemia ... Diagnosis #Management #Rheumatology
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