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differential hematology management sle causes erythematosus signs symptoms systemic table activation arthritis autoantibodies bleeding dil disease extravascular hemolysis hemolytic hemostasis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Lupusreference #druginduced ... #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... - Hemolytic anemia ... Auto-Antibodies: - ANA ... and Lupus Mimickers ... #differential #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... • Infections: Malaria ... disease, Copper and ... #hematology #anemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia ... #Rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... trapezius ridges or shoulders ... #Presentation #comparison ... #Table #Diagnosis
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... - Differential Diagnosis ... lupus anticoagulant ... of factor VII should ... #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
manifestations: from easy bruising ... SJIA], systemic lupus ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Purpura or Easy Bruising ... SLE (systemic lupus ... - Bernard—Soulier ... Meningococcal and ... peds #pediatrics #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... RF test should ... the presence of anemia ... #testing #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... & NPSLE rare, Malar ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
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