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diagnosis arthritis erythematosus disease msk systemic vasculitis workup antinuclear approach autoantibodies bone causes classification clues dermatology hematology laboratory mimickers monoarthritis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... B19 infection Malar ... lesions • Discoid lupus ... #differential # ... diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... - Hemolytic anemia ... Auto-Antibodies ... Diagnosis and Lupus ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... assay (IFA) is the main ... should be interpreted ... #rheumatology #diagnosis ... #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... pain • Swan neck ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... fingers, or pain ... the face (many differential ... erythematosus #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... XR, MRI to dx and ... dz difficult to see ... • Differentiate
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... axial (spine, shoulders ... arthritis • SLE ... Symmetrical: • RA • SLE ... #pain #Differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
• Systemic lupus ... antibodies, which ... RF test should ... the presence of anemia ... low back pain)
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... such as systemic lupus ... ) pattern: antibodies ... SLE) • Urinalysis ... #diagnosis #rheumatology
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