11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... B19 infection Malar ... • Rheumatic fever ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Anti-Mi2 Polymyalgia Rheumatica ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... differential #diagnosis #comparison ... #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
bacterial), acute rheumatic ... spondyloarthropathies, lupus ... Like in this case ... #rheumatology # ... approach #workup
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... • Immunologic Workup ... Discontinuation of causal ... #sle #comparison ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar ... • Immunologic Workup ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
axial (spine, shoulders ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... Gonorrhea • Rheumatic ... Diagnosis #MSK #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... ANAs RF test should ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ANCA-associated vasculitis, rheumatoid ... Arthritis: • Joint ... arthropathy • 90% joints ... Photosensitivity • Malar ... Erythematosus #Diagnosis #Rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... & NPSLE rare, Malar ... • Immunologic Workup ... Discontinuation of causal ... #DIL #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... vesicular eruption - Joints ... Diagnosis: Systemic rheumatic ... such as systemic lupus ... differential #diagnosis #rheumatology