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diagnosis differential dermatomyositis pain algorithm anemia antimda5 antimda5dm antinxp2 antinxp2dm bleeding bone bruising diffuse disease extravascular hemolysis hemolytic hemostasis intravascular
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... B19 infection Malar ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... BrighamChiefs #Bone #Joint ... differential #diagnosis #causes ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes ... differential #diagnosis #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
and pain of the joints ... Causes: - Idiopathic ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology ... #oncology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
, and back and shoulders ... interphalangeal joints ... Men • ~50% of cases ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... of factor VII should ... discern these causes ... Differential #Diagnosis #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... bone pain, fever, joint ... #Leukemia #Hematology ... #Oncology #Diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
, and back and shoulders ... interphalangeal joints ... Muscle atrophy may cause ... diagnosis #management #rheumatology ... #dermatology
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