13 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... muscle pain and ... uncommon 5-15% of lupus ... myopathy) VA Joint ... diagnosis #comparison #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... B19 infection Malar ... lesions • Discoid lupus ... #joint #pain #skin ... differential #diagnosis #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... BrighamChiefs #Bone #Joint ... differential #diagnosis #causes ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... disease and these should ... neurology, back pain ... cell disease Rheumatology ... discrepancy, multiple joint
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... ) Inflammatory joint ... pain (especially ... and fingers, or pain ... erythematosus #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... Neuro-muscular: vacuolar myopathy ... very uncommon but should ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Approach to Joint ... axial (spine, shoulders ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... Diagnosis #MSK #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Arthritis: • Joint ... pain • Swan neck ... arthropathy • 90% joints ... Photosensitivity • Malar ... Erythematosus #Diagnosis #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... ANAs RF test should ... , and low back pain ... diagnosis #testing #Rheumatology