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diagnosis sle blood druginduced hydroxychloroquine pharmacology product reactions adverseeffects antinxp2 antinxp2dm arthritis benefits classification comparison dermatology dermatomyositis differential dil erythematosus
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... Hydroxychloroquine #HCQ ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Manifestations: Malar ... Positive in 60-80% of cases ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Manifestations: Malar ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... very uncommon but should ... Hydroxychloroquine #hcq ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
hands/feet, knees, shoulders ... Signs & Symptoms ... Hydroxychloroquine (HCQ ... Arthritis #diagnosis #management ... #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... tested include: Malaria ... Transfusion #diagnosis #management ... #hematology #reactions
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... such as systemic lupus ... purpura: strong sign ... • HIV • HBV HCV ... differential #diagnosis #rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... tested include: Malaria ... Transfusions #diagnosis #management ... #hematology #reactions
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... & NPSLE rare, Malar ... Discontinuation of causal ... #DIL #rheumatology ... diagnosis #treatment #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
, and back and shoulders ... (in a shawl sign ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... #rheumatology #
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