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diagnosis differential arthritis erythematosus management systemic classification druginduced msk pain workup algorithm antinuclear autoantibodies comparison criteria dil disease eularacr glomerulonephritis
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
Approach to managing ... cytoplasmic antibodies ... ; SLE, systemic ... lupus erythematosus ... Algorithm #Nephrology #Peds
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... Auto-Antibodies ... : - ANA 95-100% ... autoantibodies #signs #symptoms ... #differential #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #rheumatology # ... approach #workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... context of other symptoms ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... & NPSLE rare, Malar ... Manifestations: Malar ... Workup: - ANA ... #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Arthritis: • Joint ... arthropathy • 90% joints ... Photosensitivity • Malar ... : • Symptoms limited
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
in at least 2 joints ... low C4, Low C3 and ... Highly specific antibodies ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... constitutional symptoms ... - Autoimmune Rheumatologic ... arthritis • SLE ... Symmetrical: • RA • SLE
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... • Systemic lupus ... antibodies, which ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... Presentation - Systemic Symptoms ... ) pattern: antibodies ... SLE) • Urinalysis ... differential #diagnosis #rheumatology
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