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differential algorithm management causes clinical cardiology radiology pulmonary pocus table signs comparison symptoms neurology pathophysiology classification hematology peds nephrology workup
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Thrombocytopenic Purpura ... children) • Platelets ... extremely low platelet ... Thrombocytopenic #Purpura ... Thrombocytopenia #Diagnosis
Causes of Purpura - Differential Diagnosis Disruption in Vascular Integrity: • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... - Differential Diagnosis ... C), Pigmented purpuric ... Thrombocytopenia, Platelet ... #Differential #Diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... RBC's secondary to platelet ... Thrombocytopenia • Platelet ... : Platelet Defects ... #Differential #Diagnosis
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... thrombocytopenic purpura ... Henoch—Schönlein purpura ... - Scurvy #Purpura ... peds #pediatrics #diagnosis
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Thrombocytopenic Purpura ... (TTP) Diagnosis ... secondary TMA), Platelets ... soon as TTP is diagnosed ... Thrombocytopenic #Purpura
Algorithm for the outpatient management of thrombocytopenia. (DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
enzymes, and low platelet ... thrombocytopenic purpura ... thrombocytopenic purpura ... #Diagnosis #Management
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
areas of the body Purpura ... Wet purpura is the ... lowest levels Platelet ... Diagnosis VWF ... ability to bind platelets
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Thrombocytopenia - Abnormal platelet ... Henoch Schonlein Purpura ... Non-Palpable Rash: - Purpura ... #Differential #Diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... activity is the diagnostic ... available for rapid diagnosis ... intravascular hemolysis Platelet ... and decreased platelet
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... #Coagulation #diagnosis
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