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diagnosis treatment differential hepatology rheumatology thrombocytopenia vasculitis acr2021 anticoagulation causes oncology vte workup dermatology transfusion pathophysiology thrombosis checklist cirrhosis comparison
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
resulting in excessive platelet ... abnormality is platelet ... widely varying platelet ... following: • Platelet ... #diagnosis #management
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... differential #diagnosis #hematology
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Intracranial hemorrhage Management ... children) • Platelets ... extremely low platelet ... Diagnosis #Overview #Hematology
Thromboelastography (TEG) based therapy and Management If r time prolonged -> FFP If MA low -> plts/cryoprecipitate (if
based therapy and Management ... cryoprecipitate If platelets ... < 50 - > platelet ... Thromboelastography #TEG #Management ... #Diagnosis #Hematology
Thromboelastography (TEG) Based Management - If R time prolonged -> FFP - If MA low
Thromboelastography (TEG) Based Management ... cryoprecipitate - If platelets ... < 50 -> platelet ... Thromboelastography #TEG #Management ... treatment #diagnosis #hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Differential Diagnosis Platelet ... Diagnosis #causes #Platelets ... #hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... #disorders #hematology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... concentrate - Platelets ... Hct < .005) Platelet ... pheresis - Platelets
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Differential Diagnosis Algorithm ... Thrombocytosis #Platelets ... Differential #Diagnosis #Algorithm ... #hematology
Indications for Transfusion Packed RBCs • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... Prophylactically for platelet ... not transfuse platelets ... Platelet transfusions ... #RBCs #Platelets
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