46 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... #Defects #comparison
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... Prophylactically for platelet ... not transfuse platelets ... Platelet transfusions ... Management #RBCs #Platelets
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... transfusions
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... transfusions If
Indications for Transfusion of Platelets in Neonates

#Management #Peds #Pediatrics #Platelets #Transfusion #Plateletpheresis #Thresholds #NonBleeding #Surgery
Indications for Transfusion ... of Platelets in ... Peds #Pediatrics #Platelets ... #Transfusion #Plateletpheresis
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
PLATELETS Mnemonic ... Thrombocytopenia P - Platelet ... Anemia T - Trauma, Transfusion ... S - Sepsis #PLATELETS
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
determining if transfusion ... algorithms and ... reduce number of transfusions ... amplitude • If ↓ → platelet ... deficiency → give platelets
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Thresholds for Transfusion ... of Platelets in ... #Management #Platelets ... #Transfusion #Plateletpheresis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... donor (apheresis) platelets ... , due to anti-platelet ... common following platelet ... contamination: Platelets
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Suspected HIT Algorithm ... Thrombocytopenia (platelet ... Timing of onset of platelet ... diagnosis #4Ts #algorithm