53 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... Defects #comparison #table
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Differential Diagnosis Platelet ... Reactive: • Anemia ... Diagnosis #causes #Platelets
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... concentrate - Platelets ... Hct < .005) Platelet ... pheresis - Platelets
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
PLATELETS Mnemonic ... Thrombocytopenia P - Platelet ... A - Aplastic Anemia ... S - Sepsis #PLATELETS
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Differential Diagnosis Algorithm ... hemolysis, deficiency anemia ... Thrombocytosis #Platelets ... Differential #Diagnosis #Algorithm
Summary of characteristics of Platelet Aggregation Inhibitors

#AntiPlatelet #Inhibitors #Pharmacology #Table #Overview #Interactions #Pharmacology #Cardiology
characteristics of Platelet ... #Pharmacology #Table
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... hepatomegaly • Labs: anemia ... , ↑ MCV, ↑/↓ platelets ... Differential #Diagnosis #Algorithm
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Suspected HIT Algorithm ... Thrombocytopenia (platelet ... Timing of onset of platelet ... diagnosis #4Ts #algorithm
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Transfusion of Platelets ... 100 (rarely) Stable ... nonbleeding - < 10 Stable ... #Management #Platelets
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Differential #Diagnosis #Algorithm