22 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... (e.g. renal failure ... Hydroxychloroquine #HCQ ... #rheumatology #pharmacology ... levels #lupus #management
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... side effects (e.g ... #Metformin #Pharmacology ... DM2 #diabetes #endocrinology
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
is not desired (e.g ... patients with HCM ... patients with HCM ... Bradyarrhythmias, Some cases ... comparison #table #pharmacology
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... • Higher doses cause ... cAMP/cGMP • Causes ... Vasopressors #Inotropes #Pharmacology ... #Summary #management
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... side effects (e.g ... not definitively cause ... Receptor #Agonists #Pharmacology ... DM2 #diabetes #endocrinology
OPIOID SWITCHING AND TAPERING.

Long term opioid use results in physical (and potentially psychological) dependence. Opioids should
symptoms include: chills ... sweating, anxiety, nausea ... tapering #switching #pharmacology ... #conversion #management
A practical guide to starting levothyroxine therapy
Calculate full replacement dose: 1.6 mcg/kg/day
Young, otherwise healthy patient:
 •
dose: 1.6 mcg/kg ... initiation #starting #management ... #endocrinology ... #pharmacology #hypothyroidism
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Resistance, Main Uses ... 0.375-0.75 mcg/kg ... high 10-20 mcg/kg ... Properties #Table #Pharmacology ... #Effect #Management
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Medication Guide Classes ... 0.3-0.6 units/kg ... #Medications #pharmacology ... comparison #table #endocrinology
Emergency Treatment Algorithm for Convulsive Status Epilepticus
1. ABCDEFG (ABC's and Don't Ever Forget the Glucose)
2. Airway:
for reversible cause ... Lorazepam 0.1 mg/kg ... Phenytoin 20 mg/kg ... Treatment #Algorithm #Management ... #Neurology #Pharmacology