11 results
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Vasopressors and Inotropes ... - Pharmacology ... • Higher doses cause ... cAMP/cGMP • Causes ... #Pharmacology #
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
blockers which cause ... QRS #widening #ECG ... #EKG #Pharmacology ... #Medications #Toxicology ... Differential #Drugs #Classes
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Receptor, Heart Rate/Inotropy ... Resistance, Main Uses ... /kg/min - Milrinone ... Properties #Table #Pharmacology ... Management #Comparison #Inotropes
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... is not desired (e.g ... is not desired (e.g ... #Vasopressors #Inotropes ... comparison #table #pharmacology
Toxic Alcohol Ingestion: Methanol
Solvent found in cleaning and printing solutions, adhesives, stains, paint removers,
antifreeze agent in
gasoline additive Pharmacology ... - Metabolite (eg ... toxicity, but does ... NOT cause osmolal ... Diagnosis #Management #Toxicology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... distribution (1.6 – 7 L/kg ... Clozapine is known to cause ... #Toxicity #Diagnosis ... #Pharmacology
Histamine Fish Toxicity - Inadequate refrigeration increases enzyme from bacteria on fish 
Clinical 
• Skin flushing,
Histamine Fish Toxicity ... Oral burning, nausea ... Antihistamines (e.g ... Histamine #Fish #Toxicity ... #Toxicology #Diagnosis
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
side effects (e.g ... monitor for retinal toxicity ... (increased BB toxicity ... prolonging drugs (e.g ... Hydroxychloroquine #HCQ #Pharmacology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung Toxicity ... (e.g., acute respiratory ... (e.g., chronic ... Exclude other causes ... diagnosis #management #Toxicology
Fomepizole for Acetaminophen Toxicity

 • In cases where fomepizole and NAC were administered together, evidence has
Acetaminophen Toxicity ... • In cases ... over 500-600 mg/kg ... Acetaminophen #Toxicology ... #pharmacology #