9 results
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
- Pharmacology ... Summary Vasopressors ... • Higher doses cause ... cAMP/cGMP • Causes ... #Pharmacology #
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
blockers which cause ... QRS #widening #ECG ... #EKG #Pharmacology ... #Medications #Toxicology ... Differential #Drugs #Classes
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... is not desired (e.g ... Bradyarrhythmias, Some cases ... #Vasopressors #Inotropes ... comparison #table #pharmacology
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... dose: - 0.1 mg/kg ... search for other causes ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Summary Cardiac ... force (negative inotropy ... Antiarrhythmics #Pharmacology ... Classification #Classes
Toxic Alcohol Ingestion: Methanol
Solvent found in cleaning and printing solutions, adhesives, stains, paint removers,
antifreeze agent in
gasoline additive Pharmacology ... dose = 1-2 mL/kg ... . formic acid) causes ... , but does NOT cause ... Diagnosis #Management #Toxicology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... exclude other causes ... cardiomyopathy (e.g ... hemodynamics (e.g ... therapy, including inotropes
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Lung Toxicity Summary ... pulmonary nodules and masses ... Acute toxicity (e.g ... Exclude other causes ... diagnosis #management #Toxicology
Fomepizole for Acetaminophen Toxicity

 • In cases where fomepizole and NAC were administered together, evidence has
Toxicity • In cases ... over 500-600 mg/kg ... or in cases where ... Acetaminophen #Toxicology ... #pharmacology #