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management treatment neurology syndrome hematology differential hemophagocytic hlh lymphohistiocytosis pulmonary abscess als amyotrophic barre blood cerebritis classification cns crisis cryoglobulinemia
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
stagnant hypoxia (e.g ... carrying capacity (e.g ... Hypoxia #Hypoxemia #summary ... #differential #diagnosis ... #causes #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... Drugs, Unknown cause ... management #treatment #summary ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management Summary ... • Most common cause ... Lung Abscess Pathophysiology ... • Vasculitis (e.g ... #differential #causes
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management Summary ... survival is 93-95% Pathophysiology ... at the time of diagnosis ... (e.g. incidental
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... classification #rheumatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome - Summary ... Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Guillain-Barre Diagnosis ... Barre #Syndrome #diagnosis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Syndrome (SPS) - Diagnosis ... and Management Summary ... Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... Person Syndrome - Diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Sclerosis (ALS) Summary ... lateral sclerosis Pathophysiology ... - Causes progressive ... Escorial criteria uses ... EMG: LMN Signs in
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