15 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... non-essential drug/HDS treatments ... for alternative causes ... dechallenge • Acute ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular Causes ... • Iatrogenic: DILI ... #algorithm #hepatology
Orthopedic Essentials - Spinal Trauma and Spine Classification 
DENIS THREE COLUMN CONCEPT
Anterior column:
Orthopedic Essentials ... fractures: Don't cause ... Classification ... Cauda equina Treatment ... #Orthopedics #diagnosis
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... Criteria HRS-AKI (Acute ... structural kidney injury ... HRS-NAKI (Non-Acute ... HRSAKI #HRSNAKI #hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
exclude other causes ... injury with serum ... HCV, DILI, HCC, ... goal of >21 kcal/kg ... Management #Algorithm #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
liver or renal injury ... before beginning treatment ... cardiac output - Acute ... peritonitis - Acute ... #typeb #classification
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... hemophilia type (e.g ... - Acute Bleeding ... #Management #treatment ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... pattern of liver injury ... , AIH diagnosis ... regarding need for treatment ... #Management #Hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology