19 results
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... suspicion of severe disease ... Non-accidental Injury ... splenomegaly, abnormal neurology ... Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
PT, aPTT(liver disease ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... bypass), LFT (liver disease ... #Workup #hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
• Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Anticoagulation (case ... by case) • Surgery ... Syndrome #Treatment #management ... #pharmacology # ... rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Obstructive Pulmonary Disease ... Neurologic • ... Myasthenia Gravis Pharmacologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... normal in mild cases ... hemophilia type (e.g ... #treatment #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... to local skin injury ... ) • Neurologic ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... • They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... classification #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management