45 results
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
pain, swelling, ... pain), especially ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
patellofemoral joint ... patellofemoral joint ... patellofemoral joint ... pathophysiology #diagnosis ... #signs #symptoms
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Stimulation of joint ... subchondral bone -> Pain ... nociceptors -> Pain ... pathophysiology #diagnosis ... #signs #symptoms
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... & Symptoms: • ... pain / swelling ... • synovitis; joint ... tenderness • joint
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Oligoarthritis: Joint ... pain in a few joints ... ) - Large Joint ... pathophysiology #diagnosis ... #signs #symptoms
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Internal Organs: • Joint ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Approach to Joint ... : • Joint • ... or nerve root Symptoms ... #Pain #MSK #rheumatology ... #differential #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long ... BrighamChiefs #Bone #Joint ... #differential #diagnosis ... #causes #hematology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
adrenoleukodystrophy, check point ... ketoconazole, etomidate) Symptoms ... anorexia, abdominal pain ... 60-90%), Muscle/joint ... diseases, check point
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: Commonly no signs ... urination, Abdominal pain ... weakness, Bone/joint ... pain Psychiatric ... Hyperparathyroidism #diagnosis