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diagnosis hematology management chronic classification leukemia lymphocytic myelodysplastic causes elevation hemeonc hodgkins lactate lactic lymphoma myelodysplasia syndrome syndromes typea typeb
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment ... Warm AIHA • Bone ... diagnosis #workup #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... • Bone marrow ... Allogeneic stem cell ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... with hypocellular bone ... Treatment: • Consider ... stem cell transplant ... Can progress to MDS
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Hypocellular/Hypoplastic MDS ... anemia Treatment ... #Anemia #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... • Aplastic Anemia ... factor (GCSF) treatments ... blood count with differential ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... Transformation to large cell ... Lauren Banaszak, MD ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... e.g., uptake by cells ... the critically ill ... before beginning treatment ... 30mmHg) - Severe anemia
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