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diagnosis hematology causes classification abg acid acidbase acidosis agglutinin base bloodgas cold dehydrogenase disease disorders elevated elevation hemolysis interpretation laboratory
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... , spider/snake bites ... HUS, DIC, HELLP, AS ... #Anemia #Differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... the serum that has ... disease #LDH #Lactate ... Dehydrogenase #Elevated #differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Grafts, Valves, AS ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate ... #Differential #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... #anemia #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... Haptoglobin - Low as ... anemia Indirect ... elevation Serum lactate ... WBC count and differential
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Disorders - Blood Gas ... Steps for Blood Gas ... Differentials? ... Renal failure (uremia ... - Rapid saline infusion
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... focus on improving perfusion ... Reduced tissue perfusion ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential
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