11 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... #Erythematosus ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... haemolytic Coombs positive ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... • Treatment: ... Erythematosus ( ... comparison #table #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
Infarction and Pulmonary ... associated with rheumatologic ... erythematosus. ... #Pericarditis #Symptoms ... #Signs #Presentation
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... • Malar rash - spares ... : • Symptoms limited ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
such as systemic lupus ... erythematosus, ... Presentation - Systemic Symptoms ... purpura: strong sign ... #diagnosis #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
acute respiratory symptoms ... symptomsRheumatologic ... symptoms • Pericarditis ... Inhalation of spores ... infection have positive
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... Biopsies remain positive ... Treatment of GCA ... them, but urgent rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Skin lesions • Positive ... Behcet disease) Differential ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology