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diagnosis management oncology differentiation leukemia lysis tumor tumorlysis
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... , AML, NHL → AKI ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Pathophysiology: ... have fever - ACS ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Score • CML -> AML ... ↑ Can develop leukostasis ... smear: Blasts APML ... #Leukemia #Hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... ATRA treatment Pathophysiology ... #management #hematology
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