16 results
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... Drug-Induced liver injury ... Hepatitis - Autoimmune ... #Hepatology #Diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
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Causes of Extravascular ... Cold AIHA • Alloimmune ... anemia • Acute ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Other: NAFLD, Autoimmune ... Differential #Diagnosis #Causes ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... : Autoimmune hepatitis ... specificity to elevated ... diagnosis #algorithm #hepatology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... of Elevated CK ... Levels Acute CK ... renal injury, Strenuous ... myopathy - Autoimmune
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... for alternative causes ... dechallenge • Acute ... steatosis • Autoimmune ... Diagnosis #Algorithm #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... subclinical disease to acute ... pattern of liver injury ... IgG typically elevated ... Diagnosis #Management #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... range: 18 wks - postpartum ... = nonspecific (nausea ... headache, malaise) → Acute ... Liver #Pregnancy #hepatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... Viral Infection Clinical ... Hyperbilirubinemia • Elevated ... CLL (older) • Autoimmune ... hemolytic #anemia #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... At least 3 of (Acute ... resp distress, elevated ... Transfusion #Reactions #hematology