18 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... terminal alveoli and are ... inhibitors • Injection ... Langerhans giant cells are ... Active TB: •
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... terminal alveoli and are ... inhibitors • Injection ... Langerhans giant cells are ... Active TB: •
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
LATENT TB • ... IGRA/QuantiFERON-TB ... single specimen are ... Testing #Diagnosis #Workup ... #TB #Latent #Active
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in Tuberculosis ... signs/symptoms of active ... pulmonary TB PE ... decreased reflexes Pathophysiology ... excisional biopsy - Detection
Tuberculin Skin Test Interpretation - Threshold for treatment
Induration cutoff >5mm:
 • Recent exposure to an individual
individual with active ... TB • Abnormal ... consistent with old TB ... kidney disease and are ... individuals #Tuberculosis
Tweetorial - Why do we use multiple drugs to active treat tuberculosis (TB)?

I’ve often heard it’s
multiple drugs to active ... treat tuberculosis ... (TB)? ... @tony_breu #Tuberculosis ... Medications #Tweetorial #Pathophysiology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hematology for workup ... Bx Consider reactive ... Chronic infections, TB ... Differential #Diagnosis #Algorithm
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
thrombophilias are ... surgery, trauma, active ... - No other workup ... Hypercoagulable #Workup ... hematology #diagnosis #algorithm
Priapism: Pathogenesis

 - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
Post-cavernosal venules are ... detumescence (erection-ending ... norepinephrine action ... Priapism Prolonged erection ... #Priapism #Pathophysiology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Fatigue and IBD Algorithm ... Pearls: • IDA and active ... NRH & Heme eval. re ... ileal Crohn's/resection ... have fatigue w/ active