18 results
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... with exercise/activity ... #differential # ... diagnosis #pathophysiology ... #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... Antigen-antibody complexes are ... cytokines, which activate ... #Classification ... #Pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Antigen-antibody complexes are ... tissues where they activate ... Antigen-presenting cells activate ... Tuberculin test, Graft rejection ... allergy #table #classification
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Pearls: • IDA and active ... NRH & Heme eval. re ... Receptor (sTfR) to differentiate ... ileal Crohn's/resection ... #diagnosis #management
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... PRE-SHOCK - Compensated ... water #Shock #Classification ... #management #criticalcare ... #differential
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... interferes with the activity ... mitochondrial electron ... kidney injury are ... Toxicology #Diagnosis #Management
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... tumour B cells are ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #algorithm
Tachycardia - Differential Diagnosis and Management - Narrow vs Wide, Regular vs Irregular
Narrow - Regular:
Use P
Tachycardia - Differential ... Diagnosis and Management ... • MAT. 3 types ... • AFib + Pre-excitation ... #wide #narrow #algorithm
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... signs/symptoms of active ... pulmonary TB PE ... decreased reflexes Pathophysiology ... excisional biopsy - Detection
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... myopathies, Excess exertion ... Dermatomyositis) AKI - Pathophysiology ... several times per