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rheumatology dermatology differential classification behcet cryofibrinogenemia cryoglobulins cutaneous dermpath gangrenosum gpa granulomatosis lesions manifestations oncology pathology pg photo polyangiitis rash
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... which may resemble pyoderma ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... • Autoimmune diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... purpura: strong sign ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (Clinical Dx). ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Episcleritis Signs ... , breast CA - Hematologic ... DDX: - Pyoderma ... #diagnosis #dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Nephrogenic DI Hematologic ... Vasculitis: • ... 7%, Cryoglobulinemia ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... processes: • Systemic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Diagnosis? ... wide variety of clinical ... Management of PG ... medications in most cases ... #photo #dermatology
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