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rheumatology dermatology differential classification antinxp2dm behcet cryofibrinogenemia cryoglobulins cutaneous dermatologic dermatomyositis dermpath gpa granulomatosis manifestations mixed nonhcv nonpalpable palpable pathology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis ... , causes and management ... vasculitis Clinical ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... hemopathies (4%) • Cryoglobulinemia ... #semiology #signs ... #lesions #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... , in Mixed Cryoglobulinemia ... Syndrome: • Clinical ... • Autoimmune diseases ... ) #Cryoglobulinemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... hemorrhagic skin lesions ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... /HSP • Cryoglobulinemia
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... #rash #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemic skin lesions ... tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... purpura: strong sign ... Low levels mixed cryoglobulinemia
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... , sepsis or cryoglobulinemia ... cryoglobulins • Negative causes ... Calciphylaxis • Cryoglobulinemia ... Antiphospholipid syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... ) • Cutaneous vasculitis ... : • 7%, Cryoglobulinemia ... Diagnosis #Management
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