12 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
, causes and management ... vasculitis Clinical ... with refractory disease ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... hemopathies (4%) • Cryoglobulinemia ... #semiology #signs ... lesions #diagnosis #clinical
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... • Autoimmune diseases ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... • Cogan Syndrome ... purpura: strong sign ... Low levels mixed cryoglobulinemia
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... rash #diagnosis #rheumatology
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
., due to arrhythmias ... carotid sinus syndrome ... further guide management ... orthostatic vital sign ... should be guided by clinical
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... infarction or priapism ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... • Behcet syndrome ... • Cogan syndrome