45 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
commonly through its ... Rarely dominate the clinical ... Differential Diagnosis ... • Goodpasture syndrome ... #rash #diagnosis
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... appearing during the disease ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... Vasculitis Secondary: CTD ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... response to local skin ... (Clinical Dx). ... retinal damage) • Skin ... test (this is a skin
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
syndrome, caused ... differentiating between the diagnosis ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam #Video ... #Clinical #SJS
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Differential #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Positive Coombs testing ... post infectious setting ... hemolytic #anemia #hematology
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
period AND • Meeting ... vasculitis - Skin ... test Most Common Clinical ... Wide variety of skin ... #disease #Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Sneddon-Wilkinson disease ... #Differential #Diagnosis
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
nervous system (CNS ... and less common diseases ... important, as early diagnosis ... sensorineural hearing ... MRI lesions and clinical