20 results
Positive Babinski Reflex with dorsiflexion of the big toe after stroking the sole of the foot.
This
Positive Babinski ... extensor response is normal ... alliemchristie #Babinski ... #PhysicalExam #Primitive
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... diagram shows normal ... the top is a B12-deficient ... IF-Cbl complex binds ... Causes #Diagnosis #Pathophysiology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting tests can be abnormal ... clotting factor deficiency ... Plasma → Recheck abnormal ... Patient has a factor deficiency ... diagnosis #hematology #pathophysiology
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Partial Agonist • Binds ... releases, then re-binds ... allow for the normal ... receptors, and deficient ... allow excess or deficient
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
C5-C9 Deficiency ... higher in C5-C9 deficiency ... population • C5-C9 deficient ... fatality is rare Normal ... C5C9Deficiency #Complement #pathophysiology
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... relative insulin deficiency ... In DKA, the normal ... details of the pathophysiology ... #Pathophysiology
The Effect of Zinc on the Enteral Absorption of Copper. Panel A shows how copper (Cu)
enterocyte, Cu binds ... (Zn) causes Cu deficiency ... #Pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Xerophthalmia - abnormal ... with vitamin A deficiency ... #Xeropthalmia #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... : • T4 deficiency ... leads to abnormal ... Hypothyroid #Myopathy #pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
congenital defects) -> Abnormal ... Protein C & S deficiency ... , ATIII deficiency ... Occlusion #CRAO #pathophysiology