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differential rheumatology management nephrology syndromes vasculitis acidosis aniongap antigbm autoantibodies basement causes classification giomeruiar goodpastures membrane metabolic myelitis nongap prs
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... - Differential Diagnosis ... hemorrhage + rapidly progressive ... Vasculitis - Anti-GBM ... #Diagnosis
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Diffuse skin disease ... , Pulmonary fibrosis ... III: Diffuse, Renal ... crisis, Rapid progressive ... Autoantibodies #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... polyangiitis) Anti-basement ... life-threatening diseases ... Inflammatory eye disease ... Path: rapidly progressive
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
proteinuria, Rapidly progressing ... and renal abnormalities ... affects the skin, neurologic ... is 50 years • Progressive ... immune GN (rapidly progressive
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Chronic progressive ... kidney disease ... Nonsteroidal anti-inflammatory ... #differential #diagnosis ... #causes #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... resulting in rapidly progressive ... hemorrhage Diagnosis ... Goodpastures #AntiGBM #diagnosis ... #nephrology #pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... and renal abnormalities ... glomerulonephritis) • Anti-GBM ... Urticarial Vasculitis (anti-C1q ... • Urinalysis (Renal
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
versus molecular mimicry ... IgG index • Progression ... levels • NMO-IgG (anti-AQP4 ... AntiCRMP IgG, Anti-Hu ... #management #neurology
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