339 results
Standard Heparin Reversal: Protamine
  < 30 minutes - 1 unit/100 units of heparin
  30-60
Standard Heparin ... Reversal: Protamine ... unit/100 units of heparin ... units/100 units of heparin ... #Reversal #Protamine
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
Heparin - Unfractionated ... Heparin (UFH) vs ... Low-Molecular-Weight Heparin ... reversed with protamine ... reversed with protamine
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
PCC (Kcentra) - Heparin ... /LMWH → Protamine
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Vitamin K • Heparin ... : Protamine Sulfate
Insulin Comparison Chart

Insulin Types - Onset (hours) - Peak Glycemic Effect (hours) - Duration (hours)
 •
Degludec, Aspart Protamine ... Aspart, Lispro Protamine
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Heparin, Fondaparinux ... parenteral agents (e.g. heparin ... Unfractionated heparin ... molecular weight heparin ... smaller average heparin
Heparin and Low Molecular Weight Heparin (LMWH)–Mediated Inactivation of Thrombin or Factor Xa 
 - Interaction
Heparin and Low ... Molecular Weight Heparin ... antithrombin with heparin ... Unfractionated heparin ... factor Xa #Heparin
Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

The table summarizes the recommendations for adult patients on
molecular weight heparins ... Unfractionated heparin
Heparin Induced Thrombocytopenia (HIT) - Likelihood, Diagnosis and Management
 - HIT Suspected
 - Calculate 4T Score
Heparin Induced ... - Start/Stop Heparin ... Results #HIT #Heparin
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
4T Score for Heparin-Induced ... avoid checking heparin-PF4 ... 10%) - Stop heparin ... anticoagulation with non-heparin ... 50%) - Stop heparin