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diagnosis symptoms primary psychiatry 21hydroxylasedeficiency 21ohd ankylosingspondylitis anorexianervosa bulimianervosa causes cholesteatoma cushings diabetes diabeticketoacidosis differential dka extraarticular genetics glftap gravesdisease
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
↓Phosphate • Secondary ... Symptoms: Commonly no signs ... Hyperparathyroidism #diagnosis #endocrinology ... #PTH #Primary #Secondary ... #Tertiary #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Secondary hyperthyroidism ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... / Symptoms / Complications ... Pseudo-hypopyon • Secondary ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms ... / Complications ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Causes of Secondary ... hypertension and signs ... renovascular or endocrine ... renal bruit or signs ... Vasculitis • Endocrinologic
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
• Acne • If secondary ... atrophy/weakness 4) Endocrine ... menstrual cycles 5) Secondary ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Cholesteatoma (of middle ear): Pathogenesis and clinical findings • Congenital trapping of keratinizing epithelium in middle
the middle ear Signs ... / Symptoms / Complications ... • Aural Polyp secondary ... Cholesteatoma #MiddleEar #pathophysiology ... #symptoms #signs
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