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SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... pustulosis, pustular psoriasis ... , psoriasis vulgaris ... thickening • Osteitis: pain ... Rheumatology #diagnosis #management
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Plaques • Psoriasis ... Antiphospholipid-antibody syndrome ... arthritis • Psoriatic ... dermatology #joint #pain
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
syndrome • Arthritis ... Bursitis • IBD • Psoriasis ... Tarsal tunnel syndrome ... • Compartment syndrome ... Iliotibial band syndrome
How to identify and manage orofacial pain

#Orofacial #Pain #Syndromes #Differential #Diagnosis #Management
manage orofacial pain ... #Orofacial #Pain ... #Syndromes #Differential ... #Diagnosis #Management
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint Pain ... ) • Gout • Psoriatic ... Sicca) Syndrome ... • Asymmetric (Psoriatic ... Bowel Disease) • Psoriatic
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Onycholysis - Psoriatic ... • Pitting - Psoriatic ... of digits • Psoriatic ... conditions #joint #pain
Irritable Bowel Syndrome (IBS) Treatment Algorithm

IBS-Constipation:
 • Constipation: Osmotic laxatives
 • Abdominal pain: Antispasmodics

IBS-Diarrhea:
 • Diarrhea:
Irritable Bowel Syndrome ... • Abdominal pain ... • Abdominal pain ... Irritable #Bowel #Syndrome ... IBS #Treatment #Management
Ramsay Hunt Syndrome - Herpes Zoster Oticus 
Triad:
1. Ipsilateral facial paralysis 
2. Ear pain 
3. Vesicles
Ramsay Hunt Syndrome ... Ear pain 3. ... Guillain-Barré syndrome ... • Stroke syndromes ... #RamsayHunt #Syndrome
Incomplete Spinal Cord Syndromes
Anterior Cord Syndrome:
 • Bilateral loss of motor, pain and temperature sensation below
Incomplete Spinal Cord Syndromes ... Anterior Cord Syndrome ... loss of motor, pain ... Central Cord Syndrome ... Contralateral loss of pain
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... Molecular Mimicry” • Psoriatic ... skin disorder psoriasis