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differential hyponatremia hypophosphatemia workup alkalosis causes chloride gitelman hypernatremia hypokalemia hypotonic metabolic pathophysiology physiologic table urinary urine volume
Hypophosphatemia Diagnostic Algorithm - GI Losses - Redistribution - 1° HPT - 1° Renal PO4 wasting: Hereditary, TIO, Fanconi Syndrome,
Algorithm - GI ... , TIO, Fanconi Syndrome ... Hypophosphatemia #phosphorus ... #low #diagnosis ... #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm Appropriately Low Kidney Phosphate Excretion: • Decreased GI Absorption: Chronic Diarrhea, Antacids,
- Differential Diagnosis ... Algorithm Appropriately ... Low Kidney Phosphate ... #Algorithm #nephrology ... #phosphorus #workup
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Modified Hyponatremia Algorithm ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia, Low ... #diagnosis #sodium ... #nephrology
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... • Euvolemic (Low ... , Cushing syndrome ... #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Cirrhosis, Nephrotic Syndrome ... MH/CCF/CWRU EM ... #diagnosis #causes ... #nephrology #sodium ... #low
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... alkalosis • Normal/low ... , Gitelman syndrome ... #nephrology #differential ... #diagnosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... alkalosis • Normal or low ... #diagnosis #nephrology ... #management #pathophysiology
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