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diagnosis hepatology differential management algorithm primary pbc signs syndrome treatment causes pathophysiology psc rheumatology workup abnormal alkaline alp ana antibiotic
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver Disease ... : Primary Biliary ... Cirrhosis vs Primary ... Sclerosing Cholangitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... cholestasis → Cirrhosis ... PBC Signs and Symptoms ... #Cirrhosis #PBC
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Algorithm Symptoms ... of autoimmune disease ... Diagnose PBC if 2/3 criteria
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hemochromatosis • Wilson's Disease ... • Bacterial Cholangitis ... Primary Sclerosing Cholangitis ... • Primary Biliary ... Cirrhosis #Hepatomegaly
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Most common symptoms ... - Bone symptoms ... Drugs - Primary biliary ... Cholangitis (PBC ... PSC - Other biliary
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
to multi-focal biliary ... • CHOLANGITIS ... • CIRRHOSIS - ... colorectal and hepato-biliary ... Care focuses on symptom
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Hepatic: • Cirrhosis ... • Infiltrative disease ... failure • Primary biliary ... cholangitis • ... Primary sclerosing cholangitis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... : PBC (primary biliary ... cholangitis) overlap ... interstitial lung disease ... diagnosis #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... processes like primary biliary ... cirrhosis (PBC) ... with systemic diseases ... (SLE) Signs / Symptoms
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... context of other symptoms ... • Rheumatic Diseases ... Hepatitis, Primary Biliary ... Cirrhosis, Drug-Induced
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